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Drug: Penicillin
Vaccination: Cancer Vaccines
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Total 22 results found since Jan 2013.
United States' regulatory approved pharmacotherapies for nuclear reactor explosions and anthrax-associated bioterrorism
Expert Opin Drug Saf. 2023 Aug 18:1-6. doi: 10.1080/14740338.2023.2245748. Online ahead of print.ABSTRACTINTRODUCTION: Nuclear reactor incidents and bioterrorism outbreaks are concerning public health disasters. Little is known about US Food and Drug Administration (FDA)-approved agents that can mitigate consequences of these events. We review FDA data supporting regulatory approvals of these agents.AREAS COVERED: We reviewed pharmaceutical products approved to treat Hematopoietic Acute Radiation Syndrome (H-ARS) and to treat or prevent pulmonary infections following Bacillus anthracis (anthrax) exposure. Four drugs were a...
Source: Expert Opinion on Drug Safety - August 18, 2023 Category: Drugs & Pharmacology Authors: Charles L Bennett Peter Georgantopoulos Robert Peter Gale Kevin Knopf William J Hrushesky Chadi Nabhan James O Armitage Source Type: research
Assessment of country implementation of the WHO global health sector strategy on sexually transmitted infections (2016-2021)
CONCLUSIONS: Mechanisms to support improvements to STI service delivery through national-level policy, commitment, programming and surveillance are needed to operationalize, accelerate and monitor progress towards achievement of the 2030 global STI strategy targets.PMID:35507535 | DOI:10.1371/journal.pone.0263550
Source: Cancer Control - May 4, 2022 Category: Cancer & Oncology Authors: Melanie M Taylor Teodora Wi Antonio Gerbase Soe Soe Thwin Sami Gottlieb Maria Theresa Babovic Daniel Low-Beer Monica Alonso Maeve B Mello Naoko Ishikawa Anne Brink Joumana Hermez Ahmed Sabry Saliyou Sanni Leopold Ouedraogo Bharat Rewari Mukta Sharma Nicol Source Type: research
Treponema pallidum genome sequencing from six continents reveals variability in vaccine candidate genes and dominance of Nichols clade strains in Madagascar
PLoS Negl Trop Dis. 2021 Dec 22;15(12):e0010063. doi: 10.1371/journal.pntd.0010063. Online ahead of print.ABSTRACTIn spite of its immutable susceptibility to penicillin, Treponema pallidum (T. pallidum) subsp. pallidum continues to cause millions of cases of syphilis each year worldwide, resulting in significant morbidity and mortality and underscoring the urgency of developing an effective vaccine to curtail the spread of the infection. Several technical challenges, including absence of an in vitro culture system until very recently, have hampered efforts to catalog the diversity of strains collected worldwide. Here, we p...
Source: Cancer Control - December 22, 2021 Category: Cancer & Oncology Authors: Nicole A P Lieberman Michelle J Lin Hong Xie Lasata Shrestha Tien Nguyen Meei-Li Huang Austin M Haynes Emily Romeis Qian-Qiu Wang Rui-Li Zhang Cai-Xia Kou Giulia Ciccarese Ivano Dal Conte Marco Cusini Francesco Drago Shu-Ichi Nakayama Kenichi Lee Makoto O Source Type: research
Integrated Multi-omics, Virtual Screening and Molecular Docking Analysis of Methicillin-Resistant < em > Staphylococcus aureus < /em > USA300 for the Identification of Potential Therapeutic Targets: An In-Silico Approach
In this study, staphylococcal FemA protein (P0A0A5) is subjected to structure-based virtual screening for the drug repurposing approach. There are 20 residues missing in the crystal structure of FemA, and 12 of these residues are located at the catalytic site. The missing residues are modelled, and stereochemistry is checked. FDA approved drugs available in the DrugBank database have been used in virtual screening with FemA in search of potential repurposed molecules. This approach provides us with 10 drugs that may be used in the treatment of methicillin-resistant staphylococcal mediated diseases. AutoDock 4.2 is used for...
Source: Cell Research - September 22, 2021 Category: Cytology Authors: Shakilur Rahman Amit Kumar Das Source Type: research
Top 20 Research Studies of 2020 for Primary Care Physicians
This article summarizes the top 20 research studies of 2020 identified as POEMs (patient-oriented evidence that matters), including the two most highly rated guidelines of the year on gout and chronic obstructive pulmonary disease (COPD). Regarding COVID-19, handwashing and social distancing through stay-at-home orders or quarantine measures are effective at slowing the spread of illness. Use of proper face masks (not gaiters or bandanas) is also effective at preventing trans- mission. This is important because the virus can infect others during the presymptomatic phase. Aspirin can no longer be recommended for the primary...
Source: American Family Physician - July 15, 2021 Category: Primary Care Authors: Roland Grad Mark H Ebell Source Type: research
